Our Centre for Therapeutics Discovery
offers world-class facilities
Centre staff
CTD staff are based in our Mill Hill labs. They include:
• 12 medicinal chemists
• 2 computational chemists
• 2 analytical and in-vitro DMPK specialists
• 17 assay development, screening scientists and cell pharmacologists
• 10 antibody scientists (forming the Therapeutic Antibody Group)
Compound collection
• 100,000 compound Diversity set
• 14,000 compound alpha helix mimetic set
• 7,000 compound kinase set
• 4000 natural products
• 3000 pharmacologically active tool set
• 1000 fragment screening set
Useful machinery
• Analytical LC-MS/MS for compound characterisation and ADME profiling
• ClonePix for screening and selection of cell line clones when generating assay cell lines, research antibodies or biotherapeutics
• Pharma level standard of liquid handling and screening robotic platforms
News feed
Two new collaborations with Prof Mauro Perretti at the William Harvey Research Institute, Queen Mary University of London (QMUL) launched
Collaboration launched with Prof Adrian Clark and Dr Li Chan at the William Harvey Research Institute, Queen Mary University of London
MRCT have recently launched a second collaboration with the University of Bristol in the area of pain medicine.
Substituted aminopyrimidine protein kinase B (PknB) inhibitors show activity against Mycobacterium tuberculosis